Senior Engineer, Bioinformatics

The shape of it

In the posting’s own words

As a Senior Software Engineer on the Life Sciences team, you'll build biology software that our own scientists and the wider research community can depend on, and you'll be one of the main people representing that work to computational biologists outside Anthropic.

What it asks for · 7

• Have built, released, and maintained biology software that researchers outside your own group use, with evidence of adoption you can point to (for example public repositories, package downloads, citations, or use in other groups' pipelines)
• Have deep working expertise in genomics or structural biology, including the data types, file formats, standard tools, and common failure modes of at least one of these fields
• Are proficient in Python and comfortable working with large datasets in Linux and cloud or cluster computing environments
• Practice rigorous testing and release engineering: unit and integration tests, continuous integration, validation against reference data, packaging, and versioning
• Use AI coding tools as a central part of how you build software, and can show how you verify the correctness and performance of code you did not write by hand
• Have led a technical project with multiple contributors, setting direction and reviewing others' work while continuing to write code yourself
• Can explain technical work clearly to both biologists and engineers, in writing (documentation, tutorials) and in person (talks, workshops)

Also a plus

• Depth in both genomics and structural biology
• A record as the creator or a core maintainer of a widely used open-source tool in computational biology
• Experience managing or formally leading a team of engineers or scientists
• A graduate degree in computational biology, bioinformatics, computer science, or a related field, or equivalent experience
• Proficiency in a systems language such as Rust, C++, or C, and experience with performance work on large biological datasets
• Experience building software in other areas of computational biology, such as phylogenetics, proteomics, cheminformatics, or high-throughput screen analysis
• Experience shipping software built largely with AI coding agents, building agentic systems on large language models, or training machine learning models on biological sequence or structure data

What the job covers

• Design, build, and maintain biology software in genomics and structural biology (libraries, command-line tools, pipelines, datasets, and benchmarks) for use by researchers and AI agents, inside Anthropic and externally
• Own the path from research code to public release, including testing, validation against reference data and established tools, benchmarking, documentation, and packaging, and make the call on when something is ready to ship
• Maintain what we release: triage issues, review outside contributions, and manage breaking changes
• Represent the team in the biology community through conferences, workshops, tutorials, and direct work with researchers and maintainers, and turn what you learn about their needs into priorities for the team
• Partner with the team's computational and experimental scientists to turn research code into well-tested, reusable software
• Lead the technical direction of the projects you own through design review, code review, and mentoring, and, depending on your interests and the team's needs, lead a small team
• Build with Claude and AI coding agents as your default way of working, hold agent-written code to the same standard as your own, and set the team's practices for reviewing and validating it

Tools and skills named

Words the posting leans on

• biology26×
• software20×
• code15×
• experience12×
• tools11×
• build10×
• data10×
• computational biology8×
• genomics8×
• release8×
• researchers8×
• structural biology8×
• biology software7×
• datasets7×
• large7×
• research7×

Counted from the posting after the mission statement and the legal notices are set aside. The ones near the top are the ones a screener is looking for.

More open at Anthropic

• 3P Revenue Accounting & ReportingSan Francisco, CA | Seattle, WA
• Account Executive, AI NativeNew York City, NY; San Francisco, CA | New York City, NY
• Account Executive - DNBSingapore
• Account Executive, NonprofitSan Francisco, CA | New York City, NY
• Account Executive - Public Sector (ASEAN)Singapore
• Account Executive, StartupsSan Francisco, CA | New York City, NY